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Gaussian Mixture Model Loss Functional for Brain MRI Segmentation With Deep Learning

Gaussian Mixture Model Loss Functional for Brain MRI Segmentation With Deep Learning

Year:    2022

Author:    Lianhong Ma

Journal of Information and Computing Science, Vol. 17 (2022), Iss. 2 : pp. 138–153

Abstract

Because of the excellent performance and fast speed of deep neural network, U-Net has become the most popular network framework for medical image segmentation. For various specific image segmentation tasks, researchers have proposed a series of U-Net related methods. However, on the one hand, due to the inherent limitations of convolutional neural networks, the variants of U-Net still cannot model long-range information well while maintaining detailed texture information. On the other hand, since medical images are difficult to obtain a large number of high-quality semantic pixel-level annotations, it is difficult to use supervised deep learning networks. To address these issues above, we proposed a modified U-Net structure and a Gaussian mixture model (GMM) based loss function. This modified U-Net can be well applied to brain MR image segmentation, which can not only restore the detailed information well, but also take into account the relatively large-scale local information. The proposed GMM loss can be used for unsupervised training of neural networks. It effectively alleviates the shortcomings of difficult access to medical image annotation data and improves the performance of deep neural networks. In the experiments in this paper, the GMM loss function can also be used as a regular term to assist supervised learning to achieve better results. Experimental results on brain MR images demonstrate the superior performance of the proposed model.

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Journal Article Details

Publisher Name:    Global Science Press

Language:    English

DOI:    https://doi.org/2024-JICS-22355

Journal of Information and Computing Science, Vol. 17 (2022), Iss. 2 : pp. 138–153

Published online:    2022-01

AMS Subject Headings:   

Copyright:    COPYRIGHT: © Global Science Press

Pages:    16

Keywords:    Semi-supervised learning Unsupervised Deep learning Modified U-Net Gaussian mixture model.

Author Details

Lianhong Ma