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A Stochastic Immunotherapy Model for Breast Cancer with Pulsed Chemotherapy

Year:    2025

Author:    Weipeng Zhang, Shiyu Zhang, Hang Wang

Journal of Nonlinear Modeling and Analysis, Vol. 7 (2025), Iss. 2 : pp. 463–492

Abstract

In this paper, we consider an immunotherapy model for breast cancer with stochastic perturbations and pulsed chemotherapy. By using stochastic Lyapunov analysis and the strong law of large numbers, we first prove the existence, uniqueness and the stochastic ultimate boundedness of the global positive solution for the model. Then we obtain sufficient conditions for the extinction of tumor cells and the persistence of all three kinds of cells for this model. Finally, we use numerical simulations to verify the theoretical results which are obtained in the paper.

Journal Article Details

Publisher Name:    Global Science Press

Language:    English

DOI:    https://doi.org/10.12150/jnma.2025.463

Journal of Nonlinear Modeling and Analysis, Vol. 7 (2025), Iss. 2 : pp. 463–492

Published online:    2025-01

AMS Subject Headings:   

Copyright:    COPYRIGHT: © Global Science Press

Pages:    30

Keywords:    Breast cancer persistence extinction white noise impulsive effect.

Author Details

Weipeng Zhang

Shiyu Zhang

Hang Wang