@Article{CiCP-18-4,
author = {},
title = {Multiphysics Modeling of Liver Tumor Ablation by High Intensity Focused Ultrasound},
journal = {Communications in Computational Physics},
year = {2015},
volume = {18},
number = {4},
pages = {1050--1071},
abstract = {<p style="text-align: justify;">High intensity focused ultrasound is a rapidly developing technology for
the ablation of tumors. Liver cancer is one of the most common malignancies worldwide.
Since liver has a large number of blood vessels, blood flow cooling can reduce
the necrosed volume and may cause regeneration of the tumor to occur. All cancer cells
should be ablated without damaging of the critical tissues. Today, treatment planning
tools consider liver as a homogeneous organ. This paper is a step towards the development
of surgical planning platform for a non-invasive HIFU tumor ablative therapy in
a real liver geometry based on CT/MRI image. This task requires coupling of different
physical fields: acoustic, thermal and hydrodynamic. These physical fields can influence
each other. In this paper we illustrate how a computational model can be used
to improve the treatment efficiency. In large blood vessel both convective cooling and
acoustic streaming can change the temperature considerably near blood vessel. The
whole tumor ablation took only 30 seconds in the considered simulation case, which is
very small comparing with the current treatment time of several hours. Through this
study we are convinced that high ultrasound power and nonlinear propagation effects
with appropriate treatment planning can sufficiently reduce the treatment time.</p>},
issn = {1991-7120},
doi = {https://doi.org/10.4208/cicp.171214.200715s},
url = {https://global-sci.com/article/80353/multiphysics-modeling-of-liver-tumor-ablation-by-high-intensity-focused-ultrasound}
}