The polynomials related with cubic Hermite-Padé approximation to the exponential function are investigated which have degrees at most $n,m,s$ respectively. A connection is given between the coefficients of each of the polynomials and certain hypergeometric functions, which leads to a simple expression for a polynomial in a special case. Contour integral representations of the polynomials are given. By using of the saddle point method the exact asymptotics of the polynomials are derived as $n,m,s$ tend to infinity through certain ray sequence. Some further uniform asymptotic aspects of the polynomials are also discussed.