In this paper, we introduce a new class of explicit numerical methods called the tamed stochastic Runge-Kutta-Chebyshev (t-SRKC) methods, which apply the idea of taming to the stochastic Runge-Kutta-Chebyshev (SRKC) methods. The key advantage of our explicit methods is that they can be suitable for stochastic differential equations with non-globally Lipschitz coefficients and stiffness. Under certain non-globally Lipschitz conditions, we study the strong convergence of our methods and prove that the order of strong convergence is 1/2. To show the advantages of our methods, we compare them with some existing explicit methods (including the Euler-Maruyama method, balanced Euler-Maruyama method and two types of SRKC methods) through several numerical examples. The numerical results show that our t-SRKC methods are efficient, especially for stiff stochastic differential equations.