Numerical Approximation of Hopf Bifurcation for Tumor-Immune System Competition Model with Two Delays

Numerical Approximation of Hopf Bifurcation for Tumor-Immune System Competition Model with Two Delays

Year:    2013

Author:    Jing-Jun Zhao, Jing-Yu Xiao, Yang Xu

Advances in Applied Mathematics and Mechanics, Vol. 5 (2013), Iss. 2 : pp. 146–162

Abstract

This paper is concerned with the Hopf bifurcation analysis of tumor-immune system competition model with two delays. First, we discuss the stability of state points with different kinds of delays. Then, a sufficient condition to the existence of the Hopf bifurcation is derived with parameters at different points. Furthermore, under this condition, the stability and direction of bifurcation are determined by applying the normal form method and the center manifold theory. Finally, a kind of Runge-Kutta methods is given out to simulate the periodic solutions numerically. At last, some numerical experiments are given to match well with the main conclusion of this paper.

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Journal Article Details

Publisher Name:    Global Science Press

Language:    English

DOI:    https://doi.org/10.4208/aamm.12-m1224

Advances in Applied Mathematics and Mechanics, Vol. 5 (2013), Iss. 2 : pp. 146–162

Published online:    2013-01

AMS Subject Headings:    Global Science Press

Copyright:    COPYRIGHT: © Global Science Press

Pages:    17

Keywords:    Hopf bifurcation delay tumor-immune dynamical system periodic solution.

Author Details

Jing-Jun Zhao

Jing-Yu Xiao

Yang Xu