DFT and TD-DFT Studies on a Schiff Base Containing Phenylalanine Derived from Curcumin

DFT and TD-DFT Studies on a Schiff Base Containing Phenylalanine Derived from Curcumin

Year:    2011

Author:    Ping Deng, Hai-Dong Zhang, Jun-Hao Jiang, Qi-Hua Jiang

Journal of Atomic and Molecular Sciences, Vol. 2 (2011), Iss. 1 : pp. 51–57

Abstract

The structure of a schiff base containing phenylalanine derived from curcumin has been studied by computational simulations using density functional theory (DFT) and time-dependent density functional theory (TD-DFT) at B3LYP/6-311$G^{**}$ level. According to the theoretical calculations of three tautomers, enolic tautomer (A), eneamine tautomer (B) and ketonic tautomer (C), of the schiff base molecular, the geometry, relative stability, charge density population and UV-Vis characteristics of every tautomer are investigated. The calculation results demonstrate that the eneamine tautomer (B) is the most stable one and the stability of tautomers decreases in the sequence: B>A>C. The $\lambda_{max}$ of each tautomer mainly originates from the $\pi$-$\pi$* electronic transition, involving the intramolecular charge transfer. The intramolecular proton transfer caused by electron transitions can result in the interconversion of A and B with a low energy barrier. Water can make the UV-Vis spectra of A and B exhibit remarkable red shift, increasing oscillator strength and absorption intensity. On the contrary, water can make C demonstrate a spectrum without shift, decreasing oscillator strength and absorption intensity.

You do not have full access to this article.

Already a Subscriber? Sign in as an individual or via your institution

Journal Article Details

Publisher Name:    Global Science Press

Language:    English

DOI:    https://doi.org/10.4208/jams.081910.092010a

Journal of Atomic and Molecular Sciences, Vol. 2 (2011), Iss. 1 : pp. 51–57

Published online:    2011-01

AMS Subject Headings:    Global Science Press

Copyright:    COPYRIGHT: © Global Science Press

Pages:    7

Keywords:    curcumin derivative schiff base phenylalanine density functional theory (DFT).

Author Details

Ping Deng

Hai-Dong Zhang

Jun-Hao Jiang

Qi-Hua Jiang