Simulating Biofilm Deformation and Detachment with the Immersed Boundary Method

Simulating Biofilm Deformation and Detachment with the Immersed Boundary Method

Year:    2016

Communications in Computational Physics, Vol. 19 (2016), Iss. 3 : pp. 682–732

Abstract

We apply the immersed boundary (or IB) method to simulate deformation and detachment of a periodic array of wall-bounded biofilm colonies in response to a linear shear flow. The biofilm material is represented as a network of Hookean springs that are placed along the edges of a triangulation of the biofilm region. The interfacial shear stress, lift and drag forces acting on the biofilm colony are computed by using fluid stress jump method developed by Williams, Fauci and Gaver [Disc. Contin. Dyn. Sys. B 11(2):519–540, 2009], with a modified version of their exclusion filter. Our detachment criterion is based on the novel concept of an averaged equivalent continuum stress tensor defined at each IB point in the biofilm which is then used to determine a corresponding von Mises yield stress; wherever this yield stress exceeds a given critical threshold the connections to that node are severed, thereby signalling the onset of a detachment event. In order to capture the deformation and detachment behaviour of a biofilm colony at different stages of growth, we consider a family of four biofilm shapes with varying aspect ratio. For each aspect ratio, we varied the spacing between colonies to investigate role of spatial clustering in offering protection against detachment. Our numerical simulations focus on the behaviour of weak biofilms (with relatively low yield stress threshold) and investigate features of the fluid-structure interaction such as locations of maximum shear and increased drag. The most important conclusions of this work are: (a) reducing the spacing between colonies reduces drag by from 50 to 100% and alters the interfacial shear stress profile, suggesting that even weak biofilms may be able to grow into tall structures because of the protection they gain from spatial proximity with other colonies; (b) the commonly employed detachment strategy in biofilm models based only on interfacial shear stress can lead to incorrect or inaccurate results when applied to the study of shear induced detachment of weak biofilms. Our detachment strategy based on equivalent continuum stresses provides a unified and consistent IB framework that handles both sloughing and erosion modes of biofilm detachment, and is consistent with strategies employed in many other continuum based biofilm models.

You do not have full access to this article.

Already a Subscriber? Sign in as an individual or via your institution

Journal Article Details

Publisher Name:    Global Science Press

Language:    English

DOI:    https://doi.org/10.4208/cicp.161214.021015a

Communications in Computational Physics, Vol. 19 (2016), Iss. 3 : pp. 682–732

Published online:    2016-01

AMS Subject Headings:    Global Science Press

Copyright:    COPYRIGHT: © Global Science Press

Pages:    51

Keywords:   

  1. Initial velocity and position effect on dynamics of settling particles of variable sizes

    Ghosh, Sudeshna | Panghal, Rekha | Sharma, Amit

    The European Physical Journal Plus, Vol. 139 (2024), Iss. 2

    https://doi.org/10.1140/epjp/s13360-024-04935-4 [Citations: 0]
  2. Study of gravitational sedimentation of two flexible circular shaped particles using Immersed Boundary Method

    Panghal, Rekha | Ghosh, Sudeshna | Mitra, Kishalay | Yadav, Pooja

    Chinese Journal of Physics, Vol. 88 (2024), Iss. P.647

    https://doi.org/10.1016/j.cjph.2024.01.031 [Citations: 0]
  3. Simulation of the dynamic flow field in the left ventricle of the heart during diastolic filling

    Adu, Jianhua | Yin, Lixue | Zhang, Hongmei | Xie, Shenghua | Lu, Jing

    AIP Advances, Vol. 10 (2020), Iss. 2

    https://doi.org/10.1063/1.5126470 [Citations: 1]
  4. Theoretical Insight into the Biodegradation of Solitary Oil Microdroplets Moving through a Water Column

    Kapellos, George | Paraskeva, Christakis | Kalogerakis, Nicolas | Doyle, Patrick

    Bioengineering, Vol. 5 (2018), Iss. 1 P.15

    https://doi.org/10.3390/bioengineering5010015 [Citations: 5]
  5. Variable viscosity and density biofilm simulations using an immersed boundary method, part II: Experimental validation and the heterogeneous rheology-IBM

    Stotsky, Jay A. | Hammond, Jason F. | Pavlovsky, Leonid | Stewart, Elizabeth J. | Younger, John G. | Solomon, Michael J. | Bortz, David M.

    Journal of Computational Physics, Vol. 317 (2016), Iss. P.204

    https://doi.org/10.1016/j.jcp.2016.04.027 [Citations: 14]
  6. Computational modeling of microalgal biofilm growth in heterogeneous rotating algal biofilm reactors (RABRs) for wastewater treatment

    Jones, Gerald Benjamin | Sims, Ronald C. | Zhao, Jia

    Applied Mathematical Modelling, Vol. 131 (2024), Iss. P.487

    https://doi.org/10.1016/j.apm.2024.04.021 [Citations: 1]
  7. Biofilm viscoelasticity and nutrient source location control biofilm growth rate, migration rate, and morphology in shear flow

    Nguyen, Hoa | Ybarra, Abraham | Başağaoğlu, Hakan | Shindell, Orrin

    Scientific Reports, Vol. 11 (2021), Iss. 1

    https://doi.org/10.1038/s41598-021-95542-1 [Citations: 11]
  8. Progress in Industrial Mathematics at ECMI 2021

    Immersed Boundary Models of Biofilm Spread

    Carpio, Ana | González-Albaladejo, Rafael

    2022

    https://doi.org/10.1007/978-3-031-11818-0_8 [Citations: 0]
  9. Recent Trends in Biofilm Science and Technology

    Challenges and perspectives in reactor scale modeling of biofilm processes

    Eberl, Hermann J. | Wade, Matthew J.

    2020

    https://doi.org/10.1016/B978-0-12-819497-3.00016-7 [Citations: 3]
  10. Study of gravitational sedimentation of flexible, permeable circular and planktonic particle applying the immersed boundary method

    Panghal, Rekha | Ghosh, Sudeshna

    International Journal of Sediment Research, Vol. 38 (2023), Iss. 5 P.643

    https://doi.org/10.1016/j.ijsrc.2023.05.004 [Citations: 3]
  11. Simulation of composition and mass transfer behaviour of a membrane biofilm reactor using a two dimensional multi-species counter-diffusion model

    Ghasemi, Maryam | Chang, Sheng | Eberl, Hermann J. | Sivaloganathan, Sivabal

    Journal of Membrane Science, Vol. 618 (2021), Iss. P.118636

    https://doi.org/10.1016/j.memsci.2020.118636 [Citations: 13]
  12. Critical shear stresses of Pseudomonas aeruginosa biofilms from dental unit waterlines studied using microfluidics and additional magnesium ions

    Greener, Jesse | Harvey, William Y. | Gagné-Thivierge, Cynthia | Fakhari, Sepideh | Taghavi, Seyed Mohammad | Barbeau, Jean | Charette, Steve J.

    Physics of Fluids, Vol. 34 (2022), Iss. 2

    https://doi.org/10.1063/5.0076737 [Citations: 13]
  13. Morphogenesis and oxygen dynamics in phototrophic biofilms growing across a gradient of hydraulic conditions

    Depetris, Anna | Peter, Hannes | Bordoloi, Ankur Deep | Bernard, Hippolyte | Niayifar, Amin | Kühl, Michael | de Anna, Pietro | Battin, Tom Jan

    iScience, Vol. 24 (2021), Iss. 2 P.102067

    https://doi.org/10.1016/j.isci.2021.102067 [Citations: 11]
  14. A versatile micromodel technology to explore biofilm development in porous media flows

    Papadopoulos, Christos | Larue, Anne Edith | Toulouze, Clara | Mokhtari, Omar | Lefort, Julien | Libert, Emmanuel | Assémat, Pauline | Swider, Pascal | Malaquin, Laurent | Davit, Yohan

    Lab on a Chip, Vol. 24 (2024), Iss. 2 P.254

    https://doi.org/10.1039/D3LC00293D [Citations: 2]
  15. Proceedings of the 2nd International Conference on Nonlinear Dynamics and Applications (ICNDA 2024), Volume 2

    Deflection of a Smooth Cantilever Beam Caused by Fluid Pressure Gradient: A Numerical Investigation

    Panghal, Rekha | Ghosh, Sudeshna | Sharma, Amit

    2024

    https://doi.org/10.1007/978-3-031-69134-8_36 [Citations: 0]
  16. Modeling microbial growth and dynamics

    Esser, Daniel S. | Leveau, Johan H. J. | Meyer, Katrin M.

    Applied Microbiology and Biotechnology, Vol. 99 (2015), Iss. 21 P.8831

    https://doi.org/10.1007/s00253-015-6877-6 [Citations: 51]
  17. A point process model for generating biofilms with realistic microstructure and rheology

    STOTSKY, JAY ALEXANDER | DUKIC, VANJA | BORTZ, DAVID M.

    European Journal of Applied Mathematics, Vol. 29 (2018), Iss. 6 P.1141

    https://doi.org/10.1017/S0956792518000220 [Citations: 3]
  18. Two dimensional simulations to study the relationship between settling velocity and flexibility of a particle

    Panghal, Rekha | Ghosh, Sudeshna | Sharma, Amit

    Physica Scripta, Vol. 99 (2024), Iss. 6 P.065271

    https://doi.org/10.1088/1402-4896/ad4d2b [Citations: 0]
  19. Gravitational settling of two impermeable semi-torus particles

    Ghosh, Sudeshna | Yadav, Pooja | Mitra, Kishalay | Panghal, Rekha

    Chinese Journal of Physics, Vol. 86 (2023), Iss. P.361

    https://doi.org/10.1016/j.cjph.2023.11.002 [Citations: 2]