3D Simulations of Blood Flow Dynamics in Compliant Vessels: Normal, Aneurysmal, and Stenotic Arteries

3D Simulations of Blood Flow Dynamics in Compliant Vessels: Normal, Aneurysmal, and Stenotic Arteries

Year:    2016

Communications in Computational Physics, Vol. 19 (2016), Iss. 5 : pp. 1167–1190

Abstract

Arterial diseases such as aneurysm and stenosis may result from the mechanical and/or morphological change of an arterial wall structure and correspondingly altered hemodynamics. The development of a 3D computational model of blood flow can be useful to study the hemodynamics in major blood vessels and may provide an insight into the noninvasive technique to detect arterial diseases in early stage. In this paper, we present a three-dimensional model of blood flow in the aorta, which is based on the immersed boundary method to describe the interaction of blood flow with the aortic wall. Our simulation results show that the hysteresis loop is evident in the pressure-diameter relationship of the normal aorta when the arterial wall is considered to be viscoelastic. In addition, it is shown that flow patterns and pressure distributions are altered in response to the change of aortic morphology.

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Journal Article Details

Publisher Name:    Global Science Press

Language:    English

DOI:    https://doi.org/10.4208/cicp.scpde14.20s

Communications in Computational Physics, Vol. 19 (2016), Iss. 5 : pp. 1167–1190

Published online:    2016-01

AMS Subject Headings:    Global Science Press

Copyright:    COPYRIGHT: © Global Science Press

Pages:    24

Keywords: