Quantum Chemical Calculations of Warfarin Sodium, Warfarin and Its Metabolites

Quantum Chemical Calculations of Warfarin Sodium, Warfarin and Its Metabolites

Year:    2008

Communications in Computational Physics, Vol. 4 (2008), Iss. 1 : pp. 161–176

Abstract

The structural, vibrational and electronic properties of warfarin sodium, warfarin and its metabolites have been investigated theoretically by performing the molecular mechanics (MM+ force field), the semi-empirical self-consistent-field molecular-orbital (AM1), and density functional theory calculations. The geometry of the molecules have been optimized, the vibrational dynamics and the electronic properties of the molecules have been calculated in their ground state in gas phase. 

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Journal Article Details

Publisher Name:    Global Science Press

Language:    English

DOI:    https://doi.org/2008-CiCP-7785

Communications in Computational Physics, Vol. 4 (2008), Iss. 1 : pp. 161–176

Published online:    2008-01

AMS Subject Headings:    Global Science Press

Copyright:    COPYRIGHT: © Global Science Press

Pages:    16

Keywords: