Towards a Level Set Framework for Infarction Modeling: An Inverse Problem

Towards a Level Set Framework for Infarction Modeling: An Inverse Problem

Year:    2006

International Journal of Numerical Analysis and Modeling, Vol. 3 (2006), Iss. 4 : pp. 377–394

Abstract

The purpose of this paper is to introduce a level set framework suitable for identifying heart infarctions. We do this by introducing a modified Monodomain model, and an output least squares formulation comparing simulation results with observation data. In this way we obtain a flexible methodology allowing us to approximately determine the characteristics of infarctions with rather complex geometrical properties. Our approach involves a CPU demanding minimization problem. This problem is solved by applying an adjoint equation enabling efficient differentiation of the involved cost-functional. Finally, our theoretical findings are illuminated by a series of numerical experiments.

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Journal Article Details

Publisher Name:    Global Science Press

Language:    English

DOI:    https://doi.org/2006-IJNAM-909

International Journal of Numerical Analysis and Modeling, Vol. 3 (2006), Iss. 4 : pp. 377–394

Published online:    2006-01

AMS Subject Headings:    Global Science Press

Copyright:    COPYRIGHT: © Global Science Press

Pages:    18

Keywords:    level set Monodomain model heart infarctions and inverse problems.