Bioluminescence Tomography: Biomedical Background, Mathematical Theory, and Numerical Approximation

Bioluminescence Tomography: Biomedical Background, Mathematical Theory, and Numerical Approximation

Year:    2008

Journal of Computational Mathematics, Vol. 26 (2008), Iss. 3 : pp. 324–335

Abstract

Over the last couple of years molecular imaging has been rapidly developed to study physiological and pathological processes in vivo at the cellular and molecular levels. Among molecular imaging modalities, optical imaging stands out for its unique advantages, especially performance and cost-effectiveness. Bioluminescence tomography (BLT) is an emerging optical imaging mode with promising biomedical advantages. In this survey paper, we explain the biomedical significance of BLT, summarize theoretical results on the analysis and numerical solution of a diffusion based BLT model, and comment on a few extensions for the study of BLT.

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Journal Article Details

Publisher Name:    Global Science Press

Language:    English

DOI:    https://doi.org/2008-JCM-8628

Journal of Computational Mathematics, Vol. 26 (2008), Iss. 3 : pp. 324–335

Published online:    2008-01

AMS Subject Headings:   

Copyright:    COPYRIGHT: © Global Science Press

Pages:    12

Keywords:    Biomedical imaging Bioluminescence tomography (BLT) Inverse problem Regularization Numerical approximation Error analysis.