Year: 2013
Journal of Fiber Bioengineering and Informatics, Vol. 6 (2013), Iss. 1 : pp. 23–32
Abstract
A systems approach that integrates processing, structure, property and performance relations has been used in the design of multilevel-structured fibrous materials. For electrospun fibrous structure, numerical implementation of multiscale materials philosophy provides a hierarchy of computational models defining design parameters that are integrated through computational continuum mechanics. Electrospun micro/nano (multiscale) poly(ε-caprolactone) (PCL) fibrous scaffolds were studied. The fibrous structures were evaluated for their mechanical, morphological and cell attachment properties. The cell attachment studies showed that cell activity on multi-scale scaffolds was higher compared to micro-fibrous scaffolds. These results suggest that the combination of a micro- and nano-fiber hierarchical scaffold could be more beneficial for tissue engineering applications than for individual scaffolds.
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Journal Article Details
Publisher Name: Global Science Press
Language: English
DOI: https://doi.org/10.3993/jfbi03201302
Journal of Fiber Bioengineering and Informatics, Vol. 6 (2013), Iss. 1 : pp. 23–32
Published online: 2013-01
AMS Subject Headings:
Copyright: COPYRIGHT: © Global Science Press
Pages: 10
Keywords: Electrospun PCL
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