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Numerical Simulation of Red Blood Cell Suspensions Behind a Moving Interface in a Capillary

Numerical Simulation of Red Blood Cell Suspensions Behind a Moving Interface in a Capillary

Year:    2014

Numerical Mathematics: Theory, Methods and Applications, Vol. 7 (2014), Iss. 4 : pp. 499–511

Abstract

Computational modeling and simulation are presented on the motion of red blood cells behind a moving interface in a capillary. The methodology is based on an immersed boundary method and the skeleton structure of the red blood cell (RBC) membrane is modeled as a spring network.  As by the nature of the problem, the computational domain is moving with either a designated RBC or an interface in an infinitely long two-dimensional channel with an undisturbed flow field in front of the computational domain. The tanking-treading and the inclination angle of a cell in a simple shear flow are briefly discussed for the validation purpose. We then present and discuss the results of the motion of red blood cells behind a moving interface in a capillary, which show that the RBCs with higher velocity than the interface speed form a concentrated slug behind the moving interface.

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Journal Article Details

Publisher Name:    Global Science Press

Language:    English

DOI:    https://doi.org/10.4208/nmtma.2014.1301si

Numerical Mathematics: Theory, Methods and Applications, Vol. 7 (2014), Iss. 4 : pp. 499–511

Published online:    2014-01

AMS Subject Headings:   

Copyright:    COPYRIGHT: © Global Science Press

Pages:    13

Keywords:    Red blood cells moving domain immersed boundary method.